Recombinant adeno-associated virus (rAAV) has been developed as a successful vector for both basic research and human gene Dresser therapy.However, neutralizing antibodies (NAbs) against AAV capsids can abolish AAV infectivity on target cells, reducing the transduction efficacy.Absence of AAV NAb has become a prerequisite qualification for patients
A cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection
Abstract Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies.Considering the complex life cycle of EBV, developing vaccines targeting key entry glycoproteins to elicit robust and durable adaptive immune responses may provide better protection.EBV gHgL-, gB- and gp42-specific antibod
The face inversion effect following pitch and yaw rotations: investigating the boundaries of holistic processing.
Upright faces are thought to be processed holistically.However, the range of views within which holistic processing occurs is unknown.Recent research by McKone (2008) suggests that holistic processing occurs for all yaw rotated face views (i.e.full-face through to profile).Here we examined whether holistic processing occurs for pitch, as well as ya
DISTRIBUTION OF CRAYFISH IN EUROPE AND SOME ADJOINING COUNTRIES
The distribution of crayfish in Europe is examined using information from a variety of sources mainly for the last Peaked Roofs two decades.All European countries have at least one indigenous crayfish species (ICS), many with large stocks, and most countries in Western Europe have at least one non-indigenous crayfish species (NICS).Some species ter